There is no chance, no destiny, no fate, that can circumvent or hinder or control the firm resolve of a determined soul.

The line asserts a strongly voluntarist view of human agency: steadfast intention can outmatch the forces people typically invoke to explain failure—luck (“chance”), predestination (“destiny”), or impersonal necessity (“fate”). Wilcox’s phrasing piles near-synonyms to sweep away excuses and to elevate “firm resolve” as the decisive power in a life. The “determined soul” suggests more than mere willpower; it implies an inner moral and spiritual steadiness that resists external pressures. Read in the context of popular self-help and inspirational verse, the quote functions as a credo of perseverance, encouraging readers to treat obstacles as negotiable and to locate control within character rather than circumstance.