Beauty?... To me it is a word without sense because I do not know where its meaning comes from nor where it leads to.

Picasso is rejecting “beauty” as a stable, universally intelligible standard. By calling it “a word without sense,” he treats the term as culturally inherited rhetoric rather than a reliable guide to making or judging art. The added clauses—he does not know where its meaning comes from or where it leads—suggest suspicion toward the hidden authorities behind aesthetic ideals (academies, tradition, bourgeois taste) and toward the ends they serve (decorative pleasure, conformity, moralizing). The remark aligns with modernist and avant‑garde attitudes: art’s value lies less in meeting pre-set criteria of prettiness than in discovery, intensity, truth to experience, or formal invention.