See, the problem is that God gives men a brain and a penis, and only enough blood to run one at a time.

In this bawdy, mock-theological one-liner, Williams riffs on a familiar comic premise: sexual arousal can override judgment. By framing it as a design flaw—God giving men two powerful drives but “only enough blood to run one at a time”—he turns physiology into a metaphor for divided priorities, where desire temporarily hijacks reason. The joke also satirizes cultural narratives about male impulsiveness, using exaggeration to expose how often people excuse poor decisions as inevitable biology. Its punch comes from the abrupt collision of sacred language (“God gives”) with blunt anatomy, a hallmark of Williams’s irreverent, observational style.