You’re not working with models, you’re working with real women who have, like, anatomy. Models do not have anatomy.

Mizrahi’s quip contrasts the fashion industry’s abstract ideal of “the model” with the physical reality of dressing actual bodies. By insisting on “real women” with “anatomy,” he points to the practical constraints—bones, curves, proportions, comfort, movement—that designers must accommodate when clothing is meant to be worn rather than merely displayed. The punchline (“Models do not have anatomy”) satirizes how runway standards can erase bodily specificity, treating models as near-featureless hangers for garments. The remark also implies a critique of designing for an unattainable norm: fashion that ignores real bodies risks becoming detached from everyday life and from the people it claims to serve.