You have got to change those diapers every day. When it says "six to twelve pounds" on the side of the Pampers box, they're not lying. That is all those things will hold.

In this stand-up line, Foxworthy uses a mock-literal reading of product labeling to turn everyday parenting into a punchline. The humor hinges on treating the diaper’s weight range (“six to twelve pounds”) not as the baby-size guidance it is, but as the diaper’s maximum capacity—suggesting an absurdly overfilled diaper if you don’t change it often. The joke also plays on the exhaustion and gross realities of caring for infants, where practical advice (“change diapers every day”) is delivered with deadpan exaggeration. It’s a characteristically observational bit: a familiar domestic detail becomes funny through misinterpretation, specificity (the Pampers brand), and a blunt, bodily payoff.