If pleasures are greatest in anticipation, just remember that this is also true of trouble.

The remark turns a common observation—anticipation heightens pleasure—into a caution about anxiety. Hubbard suggests that the mind’s forward-looking faculty magnifies not only delights but also fears: we often suffer twice, first in imagination and then (perhaps) in reality. The implied counsel is practical stoicism: enjoy anticipation without letting it metastasize into dread, and recognize that worry is frequently an “advance payment” on trouble that may never arrive. The symmetry of the sentence underscores the moral: if you accept anticipation as part of pleasure, you should also notice how it can distort and inflate distress.